2ⁿᵈ Edition of the Cancer R&D World Conference 2026

Abstract

Introduction: Unlike now widely used traditional methods of treatment of tumours by means of ionizing radiation and chemotherapy, the method of the use of extremely-low power electromagnetic fields (EMF) is non-ionizing and non-invasive and hence is completely deprived of any harmful side effects. The present study was undertaken in order to find out whether low-power EMFs can suppress the growth of tumour cells in vivo without the use of cytostatics.

Material and methods: The course of influence of EMFs started 3 days before transplantation in order to raise activity of the animals’ immune system.  On the fourth day, the animals (mice) were injected with sarcoma-37 and continued daily exposure for 0.5 hours for 15 days.  A generator operating in the frequency range of 38.5 -53.5 GHz was used as a source of radiation. A whole-body exposure of mice to medical radiation was conducted in the far-field zone of cone-shaped antenna in the mode of continuous generation with incident power density at the location of the object about 10 µW/cm². 

Results and discussion: After a 15-day course of irradiation was observed an inhibition of tumour growth by 33.5% compared with a control group and a sharp suppression of the level of DNA-methylation in 2.1 times. The tumour DNA has the high level of methylation (4.7 mol%), which after 0.5 hour daily exposure becomes (2.2 mol%) close to the corresponding value for health DNA (1.9 mol%). The obtained results are correlated with the spectrophotometric data.                                                                                                               

Conclusions: Microwave therapy has a number of advantages:                                                                                                         

*The cheapness and easy to work with generators of microwave and millimeter electromagnetic radiation, that do not require large screened rooms, does not require complicated settings or alignments and their small sizes that allows their use even in small clinics or hospitals.                                                                                               

*The method of application non-ionizing and non-thermal Microwaves is non-invasive and can be combined with other methods of treatment: physiotherapy, medicine.                                                                          

* The combined use of low-intensity millimeter radiation and anti-cancer drugs leads to a   significant reduction in their doses, which reduces as the cost of treatment by expensive medications,   so and reduces the likelihood of the patient intolerable side effects.                                                                                

* The antitumor effect of millimeter radiation indicates the prospects for the development of millimeter-wave therapy for clinical oncology in the treatment of malignant neoplasms without damaging other tissues, without antitumor drugs and harmful ionizing radiotherapy.

Based on the above, the application of non-ionizing and non-thermal medical radiation can be considered as a potentially new, promising and safe medical technology for early diagnostics and therapy in oncology.  Presented preliminary results have demonstrated the potential clinical application of extremely low power EMFs for clinical oncology in the treatment of malignancies without damaging other tissues and antitumor drugs and without toxic ionizing radio therapy.