Breakthroughs in cancer genetics and genomics are uncovering the genetic mutations and molecular mechanisms that drive cancer development and progression. These discoveries enable personalized treatment approaches, such as targeted therapies and precision oncology. At the Cancer Research and Development Conference 2025, we will explore how next-generation sequencing and CRISPR-based technologies are accelerating the identification of biomarkers, enhancing early detection, and improving prognostic accuracy. These advances are transforming cancer care, paving the way for more effective and tailored interventions that promise better patient outcomes.